When was this made?
This painting was produced between the years 1260 and 1285.
Many icons were brought to western Europe during the crusades, and especially after the fall of the Byzantine capital of Constantinople in the Fourth Crusade (1204). In the thirteenth century many Italian artists were inspired by these Byzantine depictions of holy figures.
Overall, this was a period of great artistic accomplishment -- and, indeed, the beginning of the Renaissance -- due to the visual traditions that began to take shape in Italy at the end of the thirteenth-century and into the fourteenth century.