Reflecting Medieval Manuscripts: RTI at Spencer Research Library

Q

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Quarto:
The word refers to one quarter the area of a full sheet of writing material. The quires of quarto volumes were typically made by folding two sheets in half, then in half again. 
 
Quire:
Quires are the gatherings or booklets  of which a book is formed. Quire numeration consists of numbers written on a gathering, usually on its final verso to help with  arrangement during binding.