Nestorianism
Nonetheless, in the Middle Ages, Nestorian Christians could be found as far East as China (see the map below). It should then be unsurprising that Prester John was widely rumored to be of the Nestorian faith. Given the theories surrounding the burial place of the Apostle Thomas, a figure closely associated with the Prester John legend, it is notable that one of the first major centers of Nestorianism was Edessa, where a school of Nestorian theology thrived until 489.
As a protected minority in the Middle East, Nestorians played a vital role in the cultural development taking place in the Arab world in the ninth and tenth centuries (Silverberg, 22). The story of medieval Nestorianism overlapped with that of the Mongol's beginning in the eleventh century, as Nestorian missionaries traveling eastward had reached Mongol provinces decades before the Mongol's systematic takeover of much of the Asian Steppe and Middle East. This explains the number of Nestorians that European travelers (from William of Rubruck to Marco Polo to Odoric of Pordenone) observed among the Mongols in their travels (even wives of the khan).
Due to its outlawed teachings and its apparently accelerating popularity across eastern locales, Nestorianism was treated in Catholic Europe as both a feared heresy (perhaps more serious than all "heresies" but that of Islam) as well as a missionary opportunity. Thus it should not be surprising that several missions to Prester John's kingdom were ordered for the ostensible purpose of converting the Nestorian Prester John to Catholicism.