Jonas Salk and the Invention of the Polio Vaccine

First trials of a polio vaccine

In 1935, Dr. Maurice Brodie and Dr. John Kolmer had both developed, separately, polio vaccines. Brodie's vaccine was an inactivated (formaldehyde-killed virus) vaccine, while Kolmer's was a live attenuated vaccine. Both trials tested their vaccines first on monkeys and then on several thousand children and both trials had poor and even some fatal results.

References:
Abraham, T. (2018). Polio: The Odyssey of Eradication. C. Hurst & Co. Publishers Ltd.

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