Chemistry & Crime: The Science Behind Solving Cases

Forensic Toxicology

Antidote
Definition

Toxicology - a multidisciplinary field involving the detection and interpretation of the presence of drugs and other potentially toxic compounds in bodily tissues and fluids (Stout, 2009).

History

Scheele's Green
In 1775, Swedish chemist, Carl Wilhelm Scheele discovered arsenic. Scheele prepared copper arsenite, which has a brilliant green color that was popularly used as a pigment.
































Chemistry

Chlorinated water converts arsenic to arsenous acid. Adding metallic zinc and heating the acid mixture produces arsine gas. When the gas comes into contact with a cold vessel, arsenic collects.
In 1821, arsenic was found in the stomach and urine of poisoned individuals. Today, it is common to collecting samples from: blood, urine, stomach contents, liver, vitreous humor, hair, and insects to detect poison.
Arsenic Candy

Common Poisons

Cyanide
Oxalic Acid
Cinnabar, or Mercury (II) sulfide, HgS
Don't be fooled by its appetizing name or appealing color! It's poisonous!
Cinnabar Mineral
AI Cinnabar

Resources

Books available at USC Libraries

Forensic Toxicology: Principles and Concepts
https://uosc.primo.exlibrisgroup.com/permalink/01USC_INST/273cgt/cdi_askewsholts_vlebooks_9780128192870

Principles of forensic toxicology
https://uosc.primo.exlibrisgroup.com/permalink/01USC_INST/hs9vaa/alma991043806798303731 

Additional Resources

ToxTutor

References

Stout, P. (2009). Information Resources in Toxicology (4th Ed).
West, J. B. (2014). Carl Wilhelm Scheele, the discoverer of oxygen, and a very productive chemist. American Journal of Physiology. Lung Cellular and Molecular Physiology, 307(11), L811–L816. https://doi.org/10.1152/ajplung.00223.2014
 

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