Lecture 20 objectives and skills
- Draw the mechanistic steps for E1 and E2 reactions.
- Understand/interpret/draw reaction coordinate diagrams.
- Use orbitals to explain the alkene stereochemistry in elimination reactions.
- Know the “Key Features” of E1 and E2 reactions.
- Explain substrate preferences for E1 vs E2.
- Predict the product(s) of E1 and E2 reactions.
- Combine all known reactions to solve synthesis problems.
Skills
- Critical assessment using abstract concepts
- Outcome predictions
- Comparisons of fine details
- Building knowledge libraries
