Lecture 14 objectives and skills
- Draw mechanistic steps for the halogenation, nitration, sulfonation, alkylation, and acylations of benzenes.
- Understand/interpret/draw reaction coordinate diagrams.
- Use orbitals to explain the stability of benzene.
- Utilize important side group modifications (amine formation, Clemmensen reduction, desulfonation, and oxidations).
- Know the “Key Features” of EArS reactions.
- Predict the product(s) for all EArs additions.
- Combine all known reactions to solve synthesis problems.
Skills
- Critical assessment using abstract concepts
- Outcome predictions
- Comparisons of fine details
- Building knowledge libraries
