Lec 7 objectives and skills
- Understand optical rotation and (+)/(-) notation.
- Describe how a polarimeter works.
- Explain the terms “optically active” and “racemic mixture”.
- Determine “ee” for enantiomeric mixtures and use “ee” values to determine molar ratios and predict observed optical rotation values.
- Determine the total number of stereoisomers.
- Draw all stereoisomers for a molecule with 2 chiral centres and assign the relationships (including meso).
- Understand the difference between chiral diastereomers and geometric diastereomers.
- Appreciate the impact of stereochemistry on biological systems.
- Visualization and manipulation of 3D geometries from 2D images
Skills
- Visualization and manipulation of 3D geometries from 2D images
- Utilization of tangible model systems
- Application of standard methods
- Comparisons of fine details
- Connection of invisible, microscopic properties to visible, macroscopic observations